Hi guys I haven't been around as I started methotrexate and plaquenel for my lupus. The first week I had the pill form, second week I did my own intramuscular injection. Word is side effects are less with injections. Good news is I haven't been naseaus with either of them bad news is they completely knock me off my feet for days. I can't think or form a sentence. The fatigue is beyond what I can put into words. Good news is with injections it happens almost right away so there's some predictability. With the pills it doesn't. I do my injections on Tuesday. I'm still feeling pretty rough today and I have to be at the market all weekend long. The meds if they're going to work take 3-6 months to do so. So now not only am I dealing with the pain and illness of lupus, I'm also dealing with the wicked side effects of the meds with no relief except perocette which takes the edge off pain for a short while, but also knocks me out. I wondering if there's anyone else on here with lupus or RA being treated with methotrexate? Oh as of last night and today dizziness is added to the mix.