DMSO is simply a solvent. By itself it will do nothing; it acts by taking stuff on your skin and causing it to be absorbed by the skin. So its effects will depend on what's on your skin. By the way, it's an urban myth that WD-40 contains DMSO, in case that was what you were thinking of trying.
Arkady, I'd have to disagree that DMSO won't do anything on its own, although it is definitely an industrial solvent.
I was actually talking to my friends about it earlier. I don't completely understand how it works, but it makes the pain bearable, and something I can deal with. You can drink it or put it on the skin, and I've had it help me walk, and move. I still hurt, but somehow it got me moving.
I wouldn't call it a pain killer, because it doesn't just make pain stop, like Kava or magnolia root, but it changed something, maybe in my mind, or the nerves, I'm not sure. There is a doc who uses IV DMSO to help certain conditions involving partial paralization, and it had been used to treat arthritis in horses.
You can get it from farm stores like wilco, and there are things you have to be careful about, like (in my case) avoiding pools with chlorine. There are others with more perspective of potential side effects on here, but my experience was close to a miracle, so I think it's worth a shot.