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OA and allergic to NSAIDS

Mar 16, 2015 5:12 PM

I have been suffering from OA in both knees for about 25 years. Twenty-three years ago I began having progressively worsening anaphylactic reactions to the NSAIDs I was prescribed (Motrin and Tolectin). Since then, my only relief has been from opioids, which I hate and which my PCP has discontinued. I am taking Cymbalta 90 mg and gabapentin 900 mg t.i.d. for other conditions, and I can't perceive much of an effect on the pain.

I have tried a couple of herbal supplements (curcumin and bromelain) that reportedly have anti-inflammatory properties, with no effect.

Has anyone had positive experience with these or other supplements for inflammation? How about acupuncture?


Mar 16, 2015 5:27 PM

Jeff, have you tried Glucosamine and chondrotin? They actually worked for a while for me.

Mar 16, 2015 6:41 PM

Jeff70, I have the exact same problems, osteoarthritis & Nsaids. But I have a huge allergy list and even had to come off of cymbalta. I use Voltaren gel a lot, directly on the joints. I also use heated & chilled rice packs (filled tube socks). I just started gabapentin, first at 300mg but because of oversedation I'm on 100 mg 2-3x day.

Mar 17, 2015 11:03 AM

Jeff70, yo may also want to try some or all of the following. Try to remove or limit the amount of gluten you eat, take B complex, magnesium with calcium, eat dark greens and fresh, organic herbs such as sage, basil, turmeric and ginger as they all have anti inflammatory properties. Chondroitan And Glucosamines are also some times beneficial. I also took the wonderful advice from FlappsyLady and use the rice in a sock and heat it in the microwave. It does help relax muscles and along with breathing exercises to relax my mind, it can help you quite a bit. I hope this is of help to you. Good luck.

Mar 19, 2015 7:11 AM

You may be allergic to NSAIDs but that doesn't mean your allergic to COX inhibitors. COX inhibitors prevent the chemicals used in Inflammation being released. COX inhibitors come in three forms COX-1, COX-2 and both

Mar 20, 2015 5:46 PM

Thanks for the feedback, all!

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